Kar Neng Lai Selected Research

NOX-D21

1/2018

Complement C5a inhibition moderates lipid metabolism and reduces tubulointerstitial fibrosis in diabetic nephropathy.

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Kar Neng Lai Research Topics

Disease

32	IGA Glomerulonephritis (IGA Nephropathy) 01/2023 - 02/2000
28	Inflammation (Inflammations) 04/2024 - 05/2002
20	Fibrosis (Cirrhosis) 01/2023 - 12/2003
14	Peritonitis 12/2020 - 11/2005
14	Proteinuria 01/2018 - 01/2002
13	Infections 12/2020 - 01/2002
12	Diabetic Nephropathies (Diabetic Nephropathy) 01/2018 - 10/2002
10	Chronic Kidney Failure (Chronic Renal Failure) 01/2021 - 12/2003
7	Chronic Renal Insufficiency 01/2023 - 08/2010
7	Albuminuria 01/2019 - 01/2010
7	Renal Insufficiency (Renal Failure) 09/2011 - 11/2003
6	Glomerulonephritis 05/2006 - 10/2002
5	Necrosis 04/2013 - 01/2003
5	Disease Progression 10/2005 - 10/2002
4	Acute Kidney Injury (Acute Renal Failure) 04/2024 - 07/2004
4	Sleep Apnea Syndromes (Sleep Apnea) 06/2010 - 09/2006
3	Ischemia 04/2024 - 06/2012
3	Type 2 Diabetes Mellitus (MODY) 01/2023 - 01/2010
3	Kidney Diseases (Kidney Disease) 11/2017 - 07/2008
3	Wounds and Injuries (Trauma) 05/2013 - 06/2008
3	Hypertrophy 05/2013 - 09/2011
3	Systemic Lupus Erythematosus (Libman-Sacks Disease) 04/2013 - 04/2005
3	Hepatitis B 10/2005 - 09/2002
2	Vascular System Injuries 01/2023 - 12/2021
2	Hyperkalemia 01/2023 - 01/2021
2	Hypoxia (Hypoxemia) 01/2023 - 11/2020
2	Neoplasms (Cancer) 12/2021 - 09/2011
2	Ureteral Obstruction 12/2021 - 11/2020
2	Reperfusion Injury 11/2020 - 10/2006
2	Hyperglycemia 03/2015 - 01/2011
2	Nephrotic Syndrome (Syndrome, Nephrotic) 07/2012 - 12/2007
2	Hematuria 02/2011 - 01/2005
2	Apnea 02/2009 - 09/2006
2	Membranous Glomerulonephritis (Membranous Nephropathy) 12/2007 - 10/2005

Drug/Important Bio-Agent (IBA)

21	Immunoglobulin A (IgA)IBA 01/2021 - 02/2000
10	CreatinineIBA 01/2023 - 01/2004
10	Transforming Growth Factor beta (TGF-beta)IBA 08/2010 - 12/2003
9	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2011 - 01/2003
8	CytokinesIBA 01/2023 - 09/2002
8	Proteins (Proteins, Gene)FDA Link 12/2021 - 01/2003
7	CollagenIBA 11/2020 - 05/2009
7	Glucose (Dextrose)FDA LinkGeneric 10/2014 - 06/2007
6	Interleukin-6 (Interleukin 6)IBA 04/2024 - 01/2008
5	Angiotensin IIIBA 08/2012 - 12/2004
5	Mycophenolic Acid (Cellcept)FDA LinkGeneric 01/2011 - 09/2002
4	AlbuminsIBA 01/2023 - 03/2010
4	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 09/2011 - 05/2009
4	Anti-Bacterial Agents (Antibiotics)IBA 09/2008 - 11/2005
4	Complement System Proteins (Complement)IBA 11/2005 - 01/2002
3	aliskiren FDA Link 01/2023 - 02/2012
3	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2023 - 07/2008
3	ReninIBA 01/2023 - 01/2011
3	CateninsIBA 12/2022 - 01/2018
3	Toll-Like Receptors (Toll-Like Receptor)IBA 03/2015 - 01/2012
3	Advanced Glycation End ProductsIBA 08/2012 - 06/2007
3	Dialysis SolutionsIBA 01/2010 - 06/2007
3	PPAR-gamma AgonistsIBA 08/2009 - 06/2006
3	PPAR gammaIBA 08/2009 - 10/2008
3	Transforming Growth Factor beta1 (TGF beta 1)IBA 05/2009 - 01/2005
3	Antigen-Antibody Complex (Immune Complex)IBA 06/2008 - 01/2003
3	Lamivudine (Epivir)FDA Link 10/2005 - 01/2002
3	Macrophage Migration-Inhibitory FactorsIBA 08/2004 - 01/2003
2	InflammasomesIBA 04/2024 - 01/2018
2	Long Noncoding RNAIBA 04/2024 - 01/2023
2	salicylhydroxamic acid (SHAM)IBA 04/2024 - 06/2012
2	Thrombin FDA Link 01/2023 - 11/2020
2	Toll-Like Receptor 4IBA 01/2023 - 01/2012
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2023 - 01/2011
2	vorapaxarIBA 01/2023 - 11/2020
2	LipopolysaccharidesIBA 12/2022 - 04/2003
2	kallistatinIBA 12/2021 - 02/2016
2	Conditioned Culture MediaIBA 01/2021 - 08/2005
2	Fibronectins (Fibronectin)IBA 11/2020 - 10/2008
2	Urea (Carbamide)FDA LinkGeneric 01/2018 - 05/2013
2	NitrogenIBA 01/2018 - 05/2013
2	Bone Morphogenetic Protein 7IBA 02/2015 - 10/2008
2	LigandsIBA 05/2013 - 01/2012
2	Antiviral Agents (Antivirals)IBA 01/2013 - 10/2005
2	LeptinIBA 08/2012 - 05/2007
2	NF-kappa B (NF-kB)IBA 08/2012 - 05/2009
2	ChemokinesIBA 08/2012 - 01/2011
2	SteroidsIBA 07/2012 - 12/2007
2	AngiotensinsIBA 01/2011 - 03/2010
2	UbiquitinIBA 08/2010 - 03/2009
2	nephrinIBA 01/2010 - 01/2009
2	Tacrolimus (Prograf)FDA LinkGeneric 12/2009 - 11/2006
2	neodymium pyrocatechin disulfonate (NPD)IBA 02/2009 - 09/2006
2	polymeric IgAIBA 10/2008 - 01/2003
2	C-Reactive ProteinIBA 07/2008 - 05/2007
2	Cytotoxins (Cytolysins)IBA 12/2007 - 09/2002
2	Serum AlbuminIBA 07/2007 - 10/2005

Therapy/Procedure

18	Peritoneal Dialysis 12/2020 - 04/2003
13	Continuous Ambulatory Peritoneal Dialysis (CAPD) 05/2009 - 04/2003
11	Therapeutics 12/2020 - 01/2002
4	Kidney Transplantation 12/2020 - 01/2002
3	Renal Dialysis (Hemodialysis) 09/2006 - 06/2003
2	Renal Replacement Therapy (Therapies, Renal Replacement) 12/2020 - 07/2007
2	Nephrectomy 09/2011 - 02/2011
2	Transplantation 09/2011 - 11/2003
2	Catheters 01/2010 - 11/2005